| 10:00 to 10:10 | Welcome and Introduction |
Jane Leeks (Newton Gateway to Mathematics) David Abrahams (University of Cambridge) |
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| Session 1: Chaired by Pras Pathmanathan (U. S. Food and Drug Administration) | 10:10 to 10:30 | Introduction | Gary Mirams (University of Nottingham) | |
| 10:30 to 10:55 | Clinical Applications of Cardiac Models | Steven Niederer (King's College London) |
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| 10:55 to 11:20 | The Role of Constraints in Metabolic Flux Analysis: Applications to Mitochondria in Cardiovascular Disease | Anna Sher (Pfizer) | ||
| 11:20 to 11:40 | Tea and coffee | |||
| Session 2: Chaired by Kylie Beattie (GlaxoSmithKline) | 11:40 to 12:05 | Modelling and Simulation for Medical Devices: When Can we Trust a Computational Model? | Pras Pathmanathan (U. S. Food and Drug Administration (FDA)) |
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| 12:05 to 12:30 | From Medical Images to Digital Twins: Technological and Translational Challenges | Tiziano Passerini (Siemens Healthineers) |
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| 12:30 to 12:55 | Numerical Solution Methods for the Heart and the Circulation | Alfio Quarteroni (EPFL - Ecole Polytechnique Fédérale de Lausanne), (Politecnico di Milano) |
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| 12:55 to 13:55 | Lunch | |||
| Session 3: Chaired by Anna Sher (Pfizer) | 13:55 to 14:20 | Cardiac Electrophysiology Modelling for Cardiac Safety Assessment | Kylie Beattie (GlaxoSmithKline) | |
| 14:20 to 14:45 | The Living Heart Project: Development of Multi-scale Computational Heart Models with Applications in Individualised Cardiovascular Care | Clint Davies-Taylor (Dassault Systémes) |
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| 14:45 to 15:10 | Enhanced Methods for Diagnosing Pharmacometric Models: Random Sampling from Conditional Distributions | Benjamin Ribba (Roche Pharmaceuticals ) | ||
| 15:10 to 15:30 | Tea and coffee | |||
| Session 4: Chaired by Gary Mirams (University of Nottingham) | 15:30 to 15:55 | Sensitivity and Uncertainty Analysis for Cardiac Cell Models | Richard Clayton (University of Sheffield) |
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| 15:55 to 16:20 | Model Order Reduction by Congruency Training in Simulations of Cardiac Mechanics | Viatcheslav Gurev (IBM Research) | ||
| 16:20 to 16:45 | Pharmacokinetic-Pharmacodynamic Modelling to Translate Cardiovascular Pharmacology from Preclinical Findings to the Clinic in Drug Development | Piet van der Graaf (Certara) |
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| 16:45 to 17:00 | Q&A and Close | Gary Mirams (University of Nottingham) | ||
| 17:00 to 18:00 | Drinks and Networking Reception |
