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9th July 2015
09:30 to 10:00 Registration, Tea and Coffee
10:00 to 10:15 Welcome and Introduction John Toland (University of Cambridge), (University of Bath), (Isaac Newton Institute)
10:15 to 10:45 Design of Experiments for IMI2 Strategic Research Agenda "The Right Prevention and Treatment for the Right Patient at the Right Time" Vladimir Dragalin (ClinResearch)
10:45 to 11:15 IDeAL (Integrated DEsign and AnaLysis of small population group trials) - A Collaborative Approach between Industry and Academia Dieter Hilgers (RWTH Aachen University)
11:15 to 11:30 Tea and Coffee
11:30 to 12:00 Accoutning for Parameter Uncertainty in Two-Stage Designs for Phase II Dose-Response Studies Bjoern Bornkamp (Novartis Institutes for Biomedical Research)
12:00 to 12:30 Adaptive Dose Finding Designs in the Presence of Model Uncertainty Tobias Mielke (Otto-von-Guericke-Universität Magdeburg)
12:30 to 13:00 Confirmatory Testing for a Beneficial Treatment Effect in Dose-Response Studies using MCP-Mod and an Adaptive Interim Analysis Franz König (Medical University of Vienna)
13:00 to 13:45 Lunch
13:45 to 14:15 Bayesian Adaptive Randomisation Revisited Andy Grieve (ClinResearch)
14:15 to 14:45 Brick Tunnel Randomisation, Overcoming Inconvenient Allocation Ratio Yevgen Tymofyeyev (Janssen Pharmaceuticals)
14:45 to 15:15 Optimal Design of Clinical Trials with Censoring Driven by Random Enrollment Valerii Fedorov (Icon PLC)
15:15 to 15:30 Tea and coffee
15:30 to 16:00 Sequential Parallel Comparision Design for Trials with High Placebo Response: Overview and Case Studies Anastasia Ivanova (University of North Carolina )
16:00 to 16:30 Regulatory Aspects of Adaptive Clinical Trial Designs: Perspectives from Scientific Advice to Marketing Authorisation Applications Frank Petavy (European Medicines Agency)
Olivier Collignon (European Medicines Agency)
16:30 to 17:00 Open Discussion and Questions Vladimir Dragalin (ClinResearch)